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Long-term consumption of sugar sweetened and artificially sweetened beverages and risk of mortality

12 / 06 / 19

Finding: Consumption of sugar sweetened beverages was positively associated with mortality, primarily through cardiovascular disease.

Summary: This study from the Harvard group analysed data from 37,716 men from the Health Professional’s Follow-up study and 80,647 women from the Nurse’s Health study. They examined associations between consumption of sugar-sweetened beverages (SSB) and artificially-sweetened beverages (ASB) and risk of total and disease-specific mortality.

After adjustment for major diet and lifestyle factors, consumption of SSBs was associated with higher risk of mortality, and hazard ratios increased with more frequent consumption (a graded association with dose). Cardiovascular disease (CVD) risk was 31% greater in the highest (>2/day) vs lowest consumption (<1/month) groups, and cancer mortality was 16% greater. ASBs were associated with total and CVD mortality in the highest intake category only (4% increase in risk).

When each cohort was analysed separately, ASBs were associated with greater risk in the female cohort only. ASBS were not associated with cancer mortality in either cohort.

Citation: Malik VS, Li Y, Pan A, De Koning L et al. Long-term consumption of sugar sweetened and artificially sweetened beverages and risk of mortality in US adults. Circulation 2019;139 (full text free)