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Research Updates | Cardiovascular disease

Effects of SSB consumption and micro and macrovascular function

12 / 09 / 17

This study assessed vascular function during acute hyperglycemia induced by consumption of commercial sugar-sweetened beverages (SSBs) and its effects on underlying mechanisms of the nitric acid pathway. Twelve healthy males consumed 600ml of water or SSB on two occasions in a single blind crossover trial and endothelial and vascular smooth muscle functions were assessed using imaging and ultrasound. Compared to water, SSB consumption impaired microvascular and macrovascular function, while vascular smooth muscle was preserved. To the authors’ knowledge, this is the first study to demonstrate the effects of acute hyperglycemia induced by SSB alone on vascular function.

Loader J, Meziat C, Watts R et al. Effects of Sugar-Sweetened Beverage Consumption on Microvascular and Macrovascular Function in a Healthy Population. Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1250-1260.