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Research Updates | Cardiovascular disease

Carbohydrate intake, Glycemic Index, Glycemic Load, and stroke: A meta-analysis of prospective cohort studies

29 / 10 / 15

Cai X, Wang C, Wang S, Cao G, Jin C, Yu J, Li X, Yan J, Wang F, Yu W, Ding F. Asia Pac J Public Health. 2015 Jul;27(5):486-96.

Study design: meta-analysis

The relationship between carbohydrate intake and cardiovascular health is a growing area of research. This meta-analysis of 7 prospective cohort studies from 6 different countries examined if there was a relationship between risk of stroke and 3 dietary factors: total carbohydrate intake, glycemic index and glycemic load.

The authors found no association with high carbohydrate intake (RR 1.12) or high glycemic index (RR1.10), but high glycemic load was a risk factor for stroke (RR 1.19).

NOTE: glycemic load is a measure of the glycemic impact of a food and is calculated as the amount of carbohydrate per serve (in grams) multiplied by the glycemic index (GI), divided by 100. It can be considered as the carbohydrate content adjusted for its glycemic index.